From Fedora Project Wiki
gnome-paint
gnome-paint is a simple, easy-to-use paint program for GNOME. Fedora 16 includes version 0.4.0. The project's web page may be found at https://launchpad.net/gnome-paint.
blender
blender has been updated to 2.5. The new release provides a number of new features, but in particular, an enhanced GUI. There is also now support of openCOLLADA for exchange 3D modelling data to other applications